The U.S. Food and Drug Administration (FDA) has issued a recall for acne treatment products from La Roche-Posay, Walgreens, and Proactiv after detecting elevated levels of benzene, a known carcinogen.
The recall follows independent lab tests confirming that several benzoyl peroxide-based skincare products contained dangerous levels of benzene, which can form when these products degrade over time or are exposed to heat.
Benzene exposure has been linked to serious health risks, including leukemia and other blood-related cancers. Despite the FDA stating that the risk remains low for most users, medical experts warn that chronic exposure could pose long-term dangers.
List of Recalled Acne Treatment Products
| Brand | Product Name | Lot Number(s) | Expiration Date |
|---|---|---|---|
| La Roche-Posay | Effaclar Duo Dual Action Acne Treatment | MYX46W | April 2025 |
| Walgreens | Acne Control Cleanser | 23 09328 | September 2025 |
| Proactiv | Emergency Blemish Relief Cream Benzoyl Peroxide 5% | V3305A, V3304A | October 2025 |
| Proactiv | Skin Smoothing Exfoliator | V4204A | July 2025 |
| SLMD | Benzoyl Peroxide Acne Lotion | 2430600 | March 2025 |
| Walgreens | Tinted Acne Treatment Cream | 49707430 | March 2026 |
| Zapzyt | Acne Treatment Gel | Voluntarily Recalled | N/A |
Consumers are urged to check their acne treatments and discontinue use if their product matches any listed above.
Why Is Benzene Dangerous?
Benzene is an industrial chemical widely used in manufacturing dyes, plastics, and detergents. It can be found in cigarette smoke, car emissions, and even some medications.
The FDA states that benzene should not be used in drug products unless absolutely necessary due to its toxicity.
Health Risks of Benzene Exposure
Medical experts warn that exposure can lead to:
- Acute Symptoms – Dizziness, headaches, confusion, tremors, and rapid heart rate.
- Long-Term Effects – Bone marrow damage, leading to anemia and immune system suppression.
- Cancer Risk – Chronic exposure increases the likelihood of leukemia and blood disorders.
| Exposure Type | Short-Term Effects | Long-Term Risks |
|---|---|---|
| Inhalation | Dizziness, headaches, drowsiness | Increased risk of leukemia, immune system damage |
| Skin Absorption | Redness, irritation | Potential long-term contamination risks |
| Oral Ingestion | Nausea, vomiting | Bone marrow suppression, blood disorders |
The World Health Organization (WHO) and Environmental Protection Agency (EPA) classify benzene as a Group 1 carcinogen, meaning it is confirmed to cause cancer in humans.
How Did Benzene Get Into Acne Products?
Dermatologists and researchers explain that benzoyl peroxide (BPO) – the active ingredient in many acne treatments – can degrade into benzene when exposed to heat, light, or improper storage conditions.
Dr. Christopher Bunick, a Yale dermatology professor, warns:
“Benzene has no safe level in skincare products. The decomposition of benzoyl peroxide into benzene is an alarming issue that needs urgent reformulation.”
The independent laboratory Valisure found that some acne products generated benzene levels far exceeding FDA safety limits, particularly when stored at temperatures above 90°F.
Storage Conditions That Worsen Benzene Formation
- Leaving products in a hot car
- Storing in humid or warm bathrooms
- Using expired acne treatments
What Should Consumers Do Next?
Consumers who have purchased any recalled acne products should take the following actions:
- Stop using the product immediately if it matches a recalled batch.
- Check for recalls on the FDA’s official website.
- Dispose of expired benzoyl peroxide products, as older formulas degrade faster.
- Store acne treatments in cool, dry places to slow benzene formation.
Refund and Replacement Options
| Brand | Refund or Replacement Policy | Contact Information |
|---|---|---|
| Proactiv | Refunds available for purchases through Proactiv.com | Contact Proactiv Customer Care |
| La Roche-Posay | Pending response from L’Oréal | Contact brand customer support |
| Walgreens | Refunds available at point of purchase | Visit nearest Walgreens store |
Consumers concerned about their skincare safety should consult a dermatologist for alternative acne treatments.
Alternative Acne Treatments Without Benzene Risk
For those looking to avoid benzoyl peroxide altogether, dermatologists recommend switching to:
- Salicylic Acid – Gently exfoliates and unclogs pores.
- Azelaic Acid – Reduces acne inflammation and kills bacteria.
- Retinoids (Adapalene, Tretinoin) – Helps with cell turnover and acne prevention.
- Tea Tree Oil or Sulfur-Based Treatments – Natural alternatives with antibacterial properties.
Dr. Marisa Garshick, a board-certified dermatologist, explains:
“Patients who are concerned about benzene should consider alternatives like salicylic acid or retinoids. There are many effective options available without the risks of benzene contamination.”
FDA’s Response and Future Regulations
The FDA continues monitoring benzene levels in consumer skincare products and urges manufacturers to reformulate acne treatments. The agency’s official statement reassured consumers that:
“Even with daily use, the risk of developing cancer from benzene in these products remains very low. However, we continue our investigation to ensure consumer safety.”
Possible Future Regulations
- Stricter benzene testing requirements for acne treatment manufacturers.
- Clearer labeling and storage instructions on BPO-based products.
- Reformulation of benzoyl peroxide treatments to prevent benzene formation.
Final Thoughts
The FDA recall of La Roche-Posay, Walgreens, and Proactiv acne products over benzene contamination highlights the importance of safe skincare choices. While the overall cancer risk remains low, consumers should stay informed, check product recalls, and explore alternative treatments.
Experts urge caution, recommending proper storage, disposal of expired acne creams, and consultation with dermatologists for safer alternatives. With regulatory actions underway, future acne treatments may see improved formulations to eliminate benzene risks altogether.
For the latest updates on product recalls, visit the FDA’s official website and stay informed about skincare safety.
